CellCelector Publications and Posters

Around the globe, the CellCelector has proven its value in applications where single cells, colonies or clones need to be identified and isolated, while providing full documented trail on the process. Many publications and posters in different applications are available. Please contact us for more information about your application.

Circulating Tumor Cells (CTCs)

• Neumann M.H. et al. Isolation and characterization of circulating tumor cells using a novel workflow combining CellSearch® and CellCelector™. Biotechnol Prog. Epub (2016). http://www.ncbi.nlm.nih.gov/pubmed/27126369
• Blassl C. et al. Gene expression profiling of single circulating tumor cells in ovarian cancer – Establishment of a multi-marker gene panel. Molecular Oncology. Epub (2016). http://www.sciencedirect.com/science/article/pii/S1574789116300175
• Schneck H. et al. EpCAM-Independent Enrichment of Circulating Tumor Cells in Metastatic Breast Cancer. PLOS One. 10(12):e0144535 (2015). http://www.ncbi.nlm.nih.gov/pubmed/26695635
• Lohr, G.J. et al. Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer. Nature Biotechnology 32, 479–484 (2014). http://www.ncbi.nlm.nih.gov/pubmed/24752078
• Yao, X. et al. Tumor cells are dislodged into the pulmonary vein during lobectomy. J Thorac Cardiovasc Surg. 148 (6), 3224-31 (2014). http://www.ncbi.nlm.nih.gov/pubmed/25172322
• Heidary, M. et al. The dynamic range of circulating tumor DNA in metastatic breast cancer. Breast Cancer Res. 16(4), 421 (2014). http://www.ncbi.nlm.nih.gov/pubmed/25107527
• Adalsteinsson, V.A. et al. Single cells from human primary colorectal tumors exhibit polyfunctional heterogeneity in secretions of ELR+ CXC chemokines. Integr. Biol. (Camb). 5(10):1272-81 (2013). http://www.ncbi.nlm.nih.gov/pubmed/23995780

Posters

• Lampignano, R. et al. The combination of Parsortix™ and CellCelector™ enables the characterisation of EpCAMneg CTCs in breast cancer. ISMRC 2016 Hamburg.
• Neumann, M. et al. CellCelector isolation of CTCs enables additional marker staining followed by panel sequencing. ISMRC 2016 Hamburg.
• Neumann, M. et al. CellCelector & CellSearch combined workflow. ACTC 2014 Crete.
• Voigt, K. et al. Single cell sequencing of rare cells after magnetic enrichment. ISRMC 2013 Paris.
• Berger, T. et al. Detection and characterization of CTCs in patients with hepatocellular carcinoma (HCC) DGHO 2013 Vienna

Single cell isolation (tumor cells, B cells, T cells, hybridomas, stem cells etc.)

• Liao M.C. et al. Single-Cell Detection of Secreted Aβ and sAPPα from Human IPSC-Derived Neurons and Astrocytes. J Neurosci. 36(5):1730-46 (2016). http://www.ncbi.nlm.nih.gov/pubmed/26843653
• Wang Y., Navin N.E. Advances and applications of single-cell sequencing technologies (Review). Molecular Cell. 58(4):598-609 (2015). http://www.ncbi.nlm.nih.gov/pubmed/26000845
• Castellarnau M. et al. Stochastic Particle Barcoding for Single-Cell Tracking and Multiparametric Analysis. Small 11(4): 489–498 (2015). http://www.ncbi.nlm.nih.gov/pubmed/25180800
• Navin, N.E. Cancer genomics: one cell at a time (Review). Genome Biol. 15(8):452 (2014). http://www.ncbi.nlm.nih.gov/pubmed/25222669
• Cornils, K et al. Multiplexing clonality-combining RGB marking and genetic barcoding. Nucl. Acid Res. 42(7), e56 (2014). http://www.ncbi.nlm.nih.gov/pubmed/24476916
• Wuethrich, I. et al. A Mouse Monoclonal Antibody Against Alexa Fluor 647. Monoclonal Antibodies in Immunodiagnosis and Immunotherapy 33(2): 109-120 (2014). http://www.ncbi.nlm.nih.gov/pubmed/24746152
• Kluth, S.M. et al. Increased Haematopoietic Supportive Function of USSC from Umbilical Cord Blood Compared to CB MSC and Possible Role of DLK-1. Stem Cells Int., 985285 (2013). http://www.ncbi.nlm.nih.gov/pubmed/23690788
• Sendra, V.G. et al. Detection and isolation of auto-reactive human antibodies from primary B cells. Methods 64(2): 153-9 (2013). http://www.ncbi.nlm.nih.gov/pubmed/23811296
• Varadarajan N.A. et al. High-throughput single-cell analysis of human CD8⁺ T cell functions reveals discordance for cytokine secretion and cytolysis. J Clin. Invest. 121(11):4322-31 (2011). http://www.ncbi.nlm.nih.gov/pubmed/21965332
• Choi, J.H. et al. Development and optimization of a process for automated recovery of single cells identified by microengraving. Biotechnol Prog. 26(3), 888-95 (2010). http://www.ncbi.nlm.nih.gov/pubmed/20063389

Posters

• Wagner, K. et al. Selection of reference genes for quantitative PCR of single cells. STS 2011

Cell colony isolation (stem cells etc.)

• Cohen, I.S. et al. DNA lesion identity drives choice of damage tolerance pathway in murine cell chromosomes. Nucl. Acids Res. 43(3):1637-45 (2015). http://www.ncbi.nlm.nih.gov/pubmed/25589543
• Shipony, Z. et al. Dynamic and static maintenance of epigenetic memory in pluripotent and somatic cells. Nature 513(7516), 115-92014 (2014). http://www.ncbi.nlm.nih.gov/pubmed/25043040
• Marx, U. et al. Automatic Production of Induced Pluripotent Stem Cells. Procedia CIRP 5, 2-6 (2013). http://www.sciencedirect.com/science/article/pii/S2212827113000024
• Haupt, S. et al. Automated selection and harvesting of pluripotent stem cell colonies. Biotechnol Appl Biochem. 59(2), 77-87 (2012). http://www.ncbi.nlm.nih.gov/pubmed/23586788
• Schneider A. et al. “The good into the pot, the bad into the crop!” – a new technology to free stem cells from feeder cells. PLoS One, 3(11), e3788 (2008). http://www.ncbi.nlm.nih.gov/pubmed/19023443
• Peterbauer T. et al. Simple and versatile methods for the fabrication of arrays of live mammalian cells. Lab Chip. 6(7), 857-63 (2006). http://www.ncbi.nlm.nih.gov/pubmed/16804589

Posters

• Planes, E. et al., Life Cell Imaging for Quality Control of Pluripotent Stem Cell Culture. ISSCR 2013 Boston

Clone picking from a semi-solid media (CHO, hybridoma, etc.)

• Gilbert, R. Fluorescent Labelling in Semi-Solid Medium to Identify High-Expressing Clones for Recombinant Protein Production (CHO). CHI’s Bioprocessing Summit, Boston 2011.
• Caron, A.W. et al. Fluorescent labeling in semi-solid medium for selection of mammalian cells secreting high-levels of recombinant proteins (CHO). BMC Biotechnol. 9, 42 (2009). http://www.ncbi.nlm.nih.gov/pubmed/19432976
• Zoldan et al. Automated clonal selection of high-producing hybridoma colonies. (Appl. Note)
• BSI – Antigen specific antibody-producing clones selected by isotypes (Appl. Note)